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RO 3280
CAS No. 1062243-51-9
RO 3280 ( RO3280; RO-3280; RO 3280; Ro5203280 )
Catalog No. M10275 CAS No. 1062243-51-9
RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1)
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 88 | In Stock |
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| 5MG | 131 | In Stock |
|
| 10MG | 178 | In Stock |
|
| 25MG | 388 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRO 3280
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NoteResearch use only, not for human use.
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Brief DescriptionRO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1)
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DescriptionRO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3nM.
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SynonymsRO3280; RO-3280; RO 3280; Ro5203280
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PathwayCell Cycle/DNA Damage
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TargetPLK
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RecptorPLK1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1062243-51-9
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Formula Weight543.61
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Molecular FormulaC27H35F2N7O3
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Purity>98%(HPLC)
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SolubilityEthanol: 100 mg/mL (183.95 mM); DMSO: 100 mg/mL (183.95 mM)
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SMILESO=C(NC1CCN(C)CC1)C2=CC=C(NC3=NC=C(N4C)C(N(C5CCCC5)CC(F)(F)C4=O)=N3)C(OC)=C2
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Chemical Name4-((9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chen S, et al. Bioorg Med Chem Lett, 2012, 22(2), 1247-1250.
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